Alternative Splicing Regulation Impacts Heart Development
نویسنده
چکیده
SR proteins serve multiple roles in the posttranscriptional control of gene expression, including as regulators of alternative splicing. In this issue of Cell, Xu et al. (2005) demonstrate that a heart-specific knockout of one SR protein, ASF/SF2, produces cardiomyopathy and misregulation of specific alternative splicing events during early postnatal development.
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ورودعنوان ژورنال:
- Cell
دوره 120 شماره
صفحات -
تاریخ انتشار 2005